PRO newsletter detail
Bruxism risk in children & adolescents with ADHD — systematic review & meta-analysis
PRO deep dive — expanded notes aligned with the five card PMIDs for this run.
Evidence Map
This issue at a glance
PRO deep dive - sleep/bruxism, atopic-ADHD symptom fluctuation, physical activity, EEG TBR, and family pathways are expanded around five PubMed anchors. Card 02 follows PMID 31020405 to match newsletter-index and A-site references.
Souto-Souza and colleagues reviewed 32 observational studies on ADHD and bruxism in children and adolescents. The evidence base included 2,629 participants with ADHD and 1,739 with bruxism, covering both sleep and awake bruxism.
Bruxism odds were higher among youth with a confirmed ADHD diagnosis, but heterogeneity was substantial and the awake-bruxism estimate had a wide confidence interval. ADHD signs without diagnostic confirmation were not significantly associated. Use this as a sleep/dental screening question, not as an ADHD test.
PubMed: 32554210van der Schans and colleagues followed 21 ADHD patients aged 7-16 years for up to 50 days using parent daily online questionnaires. The study modeled daily fluctuations in asthma/allergic rhinitis symptoms and ADHD symptoms; VAR models could be built for 16 participants.
Most modeled participants showed significant links between atopic and ADHD symptom fluctuations, but the temporal direction differed by person. This does not show that allergy causes ADHD. It supports using symptom diaries, sleep notes, and medication context as material for clinical discussion.
PubMed: 31020405This meta-analysis summarizes physical-activity interventions for elementary-school children diagnosed with ADHD, focusing on cognition, behavior, and hyperactivity symptoms. Included trials varied in exercise type, duration, frequency, and outcome measurement.
Positive signals were reported for some behavioral and general ADHD-symptom outcomes, while executive cognition and attention findings were not uniformly significant. Read physical activity as a possible supportive routine to discuss with professionals, not as a substitute for individualized care.
PubMed: 41274012van Dijk and colleagues tested whether different spectral-analysis algorithms explain inconsistent theta/beta ratio findings in ADHD. The algorithms produced different TBR values.
The key caution is that, in the analyzed datasets, TBR did not reliably distinguish ADHD from controls. TBR should not be treated as a stand-alone diagnostic biomarker; method, recording context, and clinical assessment remain essential.
PubMed: 32436141Jendreizik and colleagues analyzed data from 555 children with ADHD in the ESCAschool study, mean age 8.9 years and 80.5% boys. Structural equation modeling tested family adversity, parental psychopathology, positive and negative parenting, ADHD symptoms, and ODD symptoms.
Family adversity and parental psychopathology were associated with both ADHD and ODD symptoms, while negative parenting was mainly related to ODD symptoms. Family adversity acted indirectly through parental psychopathology and negative parenting. Use this to map support needs, not to assign blame.
PubMed: 36461089Question draft
- Which functional domain breaks down most repeatedly?
- Have sleep, allergy symptoms, family stress, and parent executive-function load been tracked as context?
- Have source design and limits been checked before turning the item into a consultation question?
| Card | Source | Check |
|---|---|---|
| 001 | PMID 32554210 | Recheck original link and study design |
| 002 | PMID 31020405 | Recheck original link and study design |
| 003 | PMID 41274012 | Recheck original link and study design |
| 004 | PMID 32436141 | Recheck original link and study design |
| 005 | PMID 36461089 | Recheck original link and study design |
Safety notice
- Recheck source links, PMIDs, and DOIs in the original records.
- This page summarizes research and does not provide diagnosis, treatment, prescription, or medication-switching instructions.
Disclaimer - It does not replace professional care.